Traumatic Acid

Traumatic Acid is a wound healing agent and a cytokinin (phytohormone) . Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].

Product Specifications

CAS Number

[6402-36-4]

Product Name Alternative

Rovamycin,Rovamycin (hexanedioate)

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/traumatic-acid.html

Concentration

10mM

Purity

99.27

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/CCCCCCCCC(O)=O

Molecular Formula

C12H20O4

Molecular Weight

228.28

Precautions

H315, H319

References & Citations

[1]Jabłońska-Trypuć A, et al. Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts.Lipids. 2016 Sep;51 (9) :1021-35.|[2]Jabłońska-Trypuć A, et al. Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells. Regul Toxicol Pharmacol. 2019 Aug;106:137-146.