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MMP17 Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Synonyms

MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4.

Gene ID

4326

Swiss Prot

Q9ULZ9

Cellular Locus

Extracellular, Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

MMP17

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human MMP17

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4326

Isotype

IgG

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