IL-23 Recombinant Antibody
Product Specifications
Background
Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.
Synonyms
IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF.
Gene ID
51561
Swiss Prot
Q9NPF7
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Target
IL-23
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human IL 23A
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51561
Isotype
IgG
Curated Selection
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