TRBP Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Required for formation of the RNA induced silencing complex (RISC) . Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2.
Synonyms
LOQS; Prbp; tarbp2; TRBP; TRBP1; TRBP2.
Gene ID
6895
Swiss Prot
Q15633
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TRBP
Clonality
Recombinant
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human TARBP2
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6895
Isotype
IgG
Curated Selection
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