GCSAM Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
Synonyms
GCAT2; Gcet; Gcsam; hGAL; M17; M17 L.
Gene ID
257144
Swiss Prot
Q8N6F7
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
GCSAM
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human GCSAM
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
257144
Isotype
IgG
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