EHMT2 Recombinant Antibody, PE Conjugated
Product Specifications
Background
Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication.
Synonyms
Bat8; Ehmt2; Euchromatic histone lysine methyltransferase 2; G9a protein; GAT8; Histone H3 K9 methyltransferase 3; NG36.
Gene ID
10919
Swiss Prot
Q96KQ7
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
EHMT2
Clonality
Recombinant
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human EHMT2
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10919
Isotype
IgG
Curated Selection
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