PU.1/Spi1 Recombinant Antibody
Product Specifications
Background
Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions.
Synonyms
Oncogene spi1; PU.1; SFPI1; SPI 1; SPI A; Spi1.
Gene ID
6688
Swiss Prot
P17947
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
PU.1/Spi1
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human SPI1
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
6688
Isotype
IgG
Curated Selection
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