SAMHD1/MOP5 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells .
Synonyms
SAMHD1; AGS5; CHBL2; DCIP; HDDC1; MOP-5; MOP5; SBBI88; Mg11.
Gene ID
25939
Swiss Prot
Q9Y3Z3
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
SAMHD1/MOP5
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human SAMHD1
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
25939
Isotype
IgG
Curated Selection
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