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SAMHD1/MOP5 Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells .

Synonyms

SAMHD1; AGS5; CHBL2; DCIP; HDDC1; MOP-5; MOP5; SBBI88; Mg11.

Gene ID

25939

Swiss Prot

Q9Y3Z3

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

SAMHD1/MOP5

Clonality

Recombinant

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human SAMHD1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

25939

Isotype

IgG

Curated Selection

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