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ELOVL1-IN-3

ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD) [1].

Product Specifications

CAS Number

2761063-99-2

UNSPSC

12352005

Target

ELOVL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/elovl1-in-3.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[C@@H]1(C2=CC=CC=C2)OCCN(C3=CC(O[C@@H]4C[C@H](N5C=CC=N5)C4)=NC=N3)C1

Molecular Formula

C21H23N5O2

Molecular Weight

377.44

References & Citations

[1]Boyd MJ, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64 (24) :17777-17794.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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