Heparanase Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety.
Synonyms
HEP; Heparanase; Heparanase1; Hpa 1; HPA; Hpa1 HPR1; HPSE1; HSE1.
Gene ID
10855
Swiss Prot
Q9Y251
Cellular Locus
Cytoplasm, Nucleus, Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Heparanase
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Heparanase
Applications
WB, IP
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
10855
Isotype
IgG
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