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Heparanase Recombinant Antibody

Product Specifications

Background

Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety.

Synonyms

HEP; Heparanase; Heparanase1; Hpa 1; HPA; Hpa1 HPR1; HPSE1; HSE1.

Gene ID

10855

Swiss Prot

Q9Y251

Cellular Locus

Cytoplasm, Nucleus, Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Heparanase

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Heparanase

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

10855

Isotype

IgG

Curated Selection

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