CDT2 Recombinant Antibody, APC Conjugated

Product Specifications

Background

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX (DTL) complex, also named CRL4 (CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21 (CIP1), FBH1, KMT5A and SDE2.

Synonyms

CDW1; DCAF2; Dtl; L2DTL; RAMP.

Gene ID

51514

Swiss Prot

Q9NZJ0

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CDT2

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human CDT2

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51514

Isotype

IgG

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