TRPM7 Recombinant Antibody, RBITC Conjugated
Product Specifications
Background
Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium.Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1) .
Synonyms
ALSPDC; CHAK; CHAK1; LTrpC7; TRPM7.
Gene ID
54822
Swiss Prot
Q96QT4
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TRPM7
Clonality
Recombinant
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human TRPM7
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
54822
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IRBAMLFHL1AP236200UL 200 µL
Rabbit Anti FHL1 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,ELISA) 200ul
Sign In for Pricing
View Details 
042229-APC 200 µL
SPI1, CT (SPI1, Transcription factor PU.1, 31kD-transforming protein) (APC) discontinued
Sign In for Pricing
View Details 
orb2935180-01 20 µg
Recombinant Volemys kikuchii NADH-ubiquinone oxidoreductase chain 4L (MT-ND4L)
Sign In for Pricing
View Details orb2935180-02 100 µg
Recombinant Volemys kikuchii NADH-ubiquinone oxidoreductase chain 4L (MT-ND4L)
Sign In for Pricing
View Details