TRIM25 Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
Synonyms
EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147.
Gene ID
7706
Swiss Prot
Q14258
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TRIM25
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human TRIM25
Applications
WB, IHC-P, IHC-F, IP
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7706
Isotype
IgG
Curated Selection
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