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FADD Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Synonyms

FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1.

Gene ID

14082

Swiss Prot

Q61160

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Target

FADD

Clonality

Recombinant

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from mouse Fadd

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

14082

Isotype

IgG

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