FADD Recombinant Antibody, Cy7 Conjugated

Product Specifications

Background

Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Synonyms

FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1.

Gene ID

14082

Swiss Prot

Q61160

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Target

FADD

Clonality

Recombinant

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from mouse Fadd

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

14082

Isotype

IgG

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