Sulazepam

Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research[1][2].

Product Specifications

CAS Number

[2898-13-7]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sulazepam.html

Purity

99.56

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

S=C1N(C)C2=C(C(C3=CC=CC=C3)=NC1)C=C(Cl)C=C2

Molecular Formula

C16H13ClN2S

Molecular Weight

300.81

References & Citations

[1]Ajay P Nayak, et al. OGR1-dependent regulation of the allergen-induced asthma phenotype. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321 (6) :L1044-L1054.|[2]Tonio Pera, et al. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. FASEB J. 2018 Feb;32 (2) :862-874.