Sulazepam
Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research[1][2].
Product Specifications
CAS Number
[2898-13-7]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sulazepam.html
Purity
99.56
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
S=C1N(C)C2=C(C(C3=CC=CC=C3)=NC1)C=C(Cl)C=C2
Molecular Formula
C16H13ClN2S
Molecular Weight
300.81
References & Citations
[1]Ajay P Nayak, et al. OGR1-dependent regulation of the allergen-induced asthma phenotype. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321 (6) :L1044-L1054.|[2]Tonio Pera, et al. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. FASEB J. 2018 Feb;32 (2) :862-874.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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