RNF8 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.
Synonyms
C3HC4 type zinc finger protein; RNF8.
Gene ID
9025
Swiss Prot
O76064
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
RNF8
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human RNF8
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
9025
Isotype
IgG
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