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TRADD Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD.Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Synonyms

AA930854; TNFR1 associated DEATH domain protein; tradd.

Gene ID

8717

Swiss Prot

Q15628

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

TRADD

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human TRADD

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Prediction Reactivity

Mouse, Rat

Gene ID URL

8717

Isotype

IgG

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