TRADD Recombinant Antibody
Product Specifications
Background
Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD.Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Synonyms
AA930854; TNFR1 associated DEATH domain protein; tradd.
Gene ID
8717
Swiss Prot
Q15628
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
TRADD
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TRADD
Applications
WB, IP, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
8717
Isotype
IgG
Curated Selection
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