TRPM8 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating.
Synonyms
LTrpC6; MGC2849; Transient receptor potential p8; Trp p8; Trpm8; TRPP8.
Gene ID
79054
Swiss Prot
Q7Z2W7
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
TRPM8
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human TRPM8
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
79054
Isotype
IgG
Curated Selection
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