HP1 gamma Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) . Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Synonyms

Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein; CBX3; HP1 gamma.

Gene ID

11335

Swiss Prot

Q13185

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

HP1 gamma

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human CBX3

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11335

Isotype

IgG

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