HP1 gamma Recombinant Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) . Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Synonyms
Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein; CBX3; HP1 gamma.
Gene ID
11335
Swiss Prot
Q13185
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
HP1 gamma
Clonality
Recombinant
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human CBX3
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
11335
Isotype
IgG
Curated Selection
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