Phospho-CHEK2 (Ser33 + Ser35) Recombinant Antibody, APC Conjugated
Product Specifications
Background
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks.
Synonyms
Cds1; Checkpoint kinase 2; Chek2; hCds1; LFS2; RAD53; Serine/threonine protein kinase Chk2.
Gene ID
11200
Swiss Prot
O96017
Modification Site
Ser33 + Ser35
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
CHEK2 (Ser33 + Ser35)
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Chk2 around the phosphorylation site of S33/S35
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
11200
Isotype
IgG
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