Phospho-CHEK2 (Ser33 + Ser35) Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks.

Synonyms

Cds1; Checkpoint kinase 2; Chek2; hCds1; LFS2; RAD53; Serine/threonine protein kinase Chk2.

Gene ID

11200

Swiss Prot

O96017

Modification Site

Ser33 + Ser35

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

CHEK2 (Ser33 + Ser35)

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Chk2 around the phosphorylation site of S33/S35

Applications

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11200

Isotype

IgG

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