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RASSF1A Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.

Synonyms

NORE2A

Gene ID

11186

Swiss Prot

Q9NS23

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

RASSF1A

Clonality

Recombinant

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human RASSF1

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11186

Isotype

IgG

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