CYP3A4 Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) . Catalyzes the hydroxylation of carbon-hydrogen bonds.

Synonyms

CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450-PCN1; Nifedipine oxidase.

Gene ID

1576

Swiss Prot

P08684

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

CYP3A4

Clonality

Recombinant

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human Cytochrome P450 3A4

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1576

Isotype

IgG

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