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CD209/DC-SIGN Recombinant Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

Synonyms

CD209 antigen-like protein A; CDSIGN; CIRE; CLEC4L; DCSIGN; Dendritic cell specific ICAM 3 grabbing nonintegrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5.

Gene ID

30835

Swiss Prot

Q9NNX6

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

CD209/DC-SIGN

Clonality

Recombinant

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human CD209

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

30835

Isotype

IgG

Curated Selection

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