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IP3 receptor Recombinant Antibody, HRP Conjugated

Product Specifications

Background

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Synonyms

5-trisphosphate receptor; Inositol 1; InsP3R1; IP3; IP3 receptor; IP3R 1; IP3R; IP3R1; Itpr1; SCA15; SCA16; SCA29.

Gene ID

3708

Swiss Prot

Q14643

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

IP3 receptor

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human ITPR1

Applications

IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3708

Isotype

IgG

Curated Selection

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