IP3 receptor Recombinant Antibody
Product Specifications
Background
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Synonyms
5-trisphosphate receptor; Inositol 1; InsP3R1; IP3; IP3 receptor; IP3R 1; IP3R; IP3R1; Itpr1; SCA15; SCA16; SCA29.
Gene ID
3708
Swiss Prot
Q14643
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
IP3 receptor
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ITPR1
Applications
IHC-P, IHC-F, IP, IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3708
Isotype
IgG
Curated Selection
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