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PDCD4 Recombinant Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.

Synonyms

Death up-regulated gene protein; Dug; H731; Ma3; Neoplastic transformation inhibitor; Nuclear antigen H731; Pdcd4; Programmed cell death protein 4; Tis.

Gene ID

27250

Swiss Prot

Q53EL6

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PDCD4

Clonality

Recombinant

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human PDCD4

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

27250

Isotype

IgG

Curated Selection

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