ITK Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.
Synonyms
EMT; Homolog of mouse T cell itk/tsk; IL 2 inducible T cell kinase; Itk; Kinase EMT; LPFS1; LYK; PSCTK2; T cell specific kinase; TSK; Tyrosine protein kinase ITK/TSK.
Gene ID
3702
Swiss Prot
Q08881
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
ITK
Clonality
Recombinant
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human ITK
Applications
Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3702
Isotype
IgG
Curated Selection
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