ITK Recombinant Antibody, APC Conjugated
Product Specifications
Background
Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.
Synonyms
EMT; Homolog of mouse T cell itk/tsk; IL 2 inducible T cell kinase; Itk; Kinase EMT; LPFS1; LYK; PSCTK2; T cell specific kinase; TSK; Tyrosine protein kinase ITK/TSK.
Gene ID
3702
Swiss Prot
Q08881
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
ITK
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human ITK
Applications
IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3702
Isotype
IgG
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