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NrCAM Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons.

Synonyms

Bravo; hBravo; Neuronal cell adhesion molecule; Ng CAM related; NgCAM related cell adhesion molecule; Nr CAM; Nrcam.

Gene ID

4897

Swiss Prot

Q92823

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

NrCAM

Clonality

Recombinant

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human Neuronal cell adhesion molecule

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4897

Isotype

IgG

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