FRS2 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Synonyms

FGFR signaling adaptor SNT; FGFR substrate 2; FRS2; FRS2A; FRS2 alpha; SNT; SNT1; Suc 1.

Gene ID

10818

Swiss Prot

Q8WU20

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

FRS2

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human FGFR substrate 2

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10818

Isotype

IgG

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