PDK1 Recombinant Antibody

Product Specifications

Background

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.

Synonyms

Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; PDH kinase 1; Pdk1; Pyruvate dehydrogenase kinase isoform 1; Pyruvate dehydrogenase kinase, isoenzyme 1.

Gene ID

5163

Swiss Prot

Q15118

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PDK1

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human PDK1

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

5163

Isotype

IgG

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