CHD4 Recombinant Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
ATP-dependent helicase that binds and distorts nucleosomal DNA.Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:17626165, PubMed:28977666.Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination.
Synonyms
ATP dependent helicase CHD4; CHD4; Chromodomain helicase DNA binding protein 4; Mi 2 autoantigen 218 kDa protein; Mi 2b; Mi2 beta.
Gene ID
1108
Swiss Prot
Q14839
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
CHD4
Clonality
Recombinant
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human CHD4
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1108
Isotype
IgG
Curated Selection
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