WNT5A Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
Synonyms
HWNT5A; Protein Wnt5a; Wingless type MMTV integration site family member 5A; WNT 5A protein; WNT 5A protein precursor; WNT5A.
Gene ID
7474
Swiss Prot
P41221
Cellular Locus
Extracellular, Secreted
Host
Rabbit
Cross Reactivity
Human
Target
WNT5A
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Wnt5a
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7474
Isotype
IgG
Curated Selection
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