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RPE65 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore

Synonyms

LCA2; mRPE65; p63; rd12; Retinal pigment epithelium specific 61 kDa protein; RP20; RPE65; sRPE65.

Gene ID

6121

Swiss Prot

Q16518

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

RPE65

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human RPE65

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human

Gene ID URL

6121

Isotype

IgG

Curated Selection

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