PML Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum. Regulates transcription activity of ELF4.
Synonyms
Protein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19; MYL; PP8675; RNF71; TRIM19.
Gene ID
5371
Swiss Prot
P29590
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
PML
Clonality
Recombinant
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human PML
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5371
Isotype
IgG
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