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XRCC1 Recombinant Antibody

Product Specifications

Background

Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity.

Synonyms

DNA repair protein XRCC1; RCC; X ray repair complementing defective repair in chinese hamster; XRCC 1.

Gene ID

7515

Swiss Prot

P18887

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

XRCC1

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human XRCC1

Applications

WB, ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

7515

Isotype

IgG

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