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Tyrosinase Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.

Synonyms

ATN; CMM8; LB24 AB; SHEP3; SK29 AB; Tumor rejection antigen AB; TYR.

Gene ID

7299

Swiss Prot

P14679

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Tyrosinase

Clonality

Recombinant

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Tyrosinase

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7299

Isotype

IgG

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