Integrin beta 4/CD104 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.
Synonyms
CD104; gp150; Integrin beta 4 subunit; ITG B4; ITGB 4; Itgb4.
Gene ID
3691
Swiss Prot
P16144
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Integrin beta 4/CD104
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Integrin beta 4
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3691
Isotype
IgG
Curated Selection
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