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Integrin beta 4/CD104 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.

Synonyms

CD104; gp150; Integrin beta 4 subunit; ITG B4; ITGB 4; Itgb4.

Gene ID

3691

Swiss Prot

P16144

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Integrin beta 4/CD104

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Integrin beta 4

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

3691

Isotype

IgG

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