Noxa Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
Synonyms
APR; ATL-derived; NOXA; Pmaip1; Protein Noxa.
Gene ID
5366
Swiss Prot
Q13794
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Noxa
Clonality
Recombinant
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human PMAIP1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5366
Isotype
IgG
Curated Selection
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