Noxa Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Synonyms

APR; ATL-derived; NOXA; Pmaip1; Protein Noxa.

Gene ID

5366

Swiss Prot

Q13794

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Noxa

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human PMAIP1

Applications

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

5366

Isotype

IgG

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