TRF1 Recombinant Antibody, APC Conjugated

Product Specifications

Background

Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression.

Synonyms

TERF1; PIN2; TRBF1; TRF1.

Gene ID

7013

Swiss Prot

P54274

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

TRF1

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human TERF1

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse

Gene ID URL

7013

Isotype

IgG

Curated Selection

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