TRF1 Recombinant Antibody, PE Conjugated
Product Specifications
Background
Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression.
Synonyms
TERF1; PIN2; TRBF1; TRF1.
Gene ID
7013
Swiss Prot
P54274
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
TRF1
Clonality
Recombinant
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human TERF1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse
Gene ID URL
7013
Isotype
IgG
Curated Selection
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